Mercedes-Benz S-Class MPG by Year
| Year | Combined | Fuel | Cost per 100 miles | Trims | Recalls |
|---|---|---|---|---|---|
| 2027 | 14–23 | Premium gasoline | $21.56 | 4 | 0 |
| 2026 | 15–23 | Premium gasoline | $21.56 | 4 | 0 |
| 2025 | 15–24 | Premium gasoline | $20.66 | 6 | 0 |
| 2024 | 15–24 | Premium gasoline | $20.66 | 4 | 0 |
| 2023 | 14–23 | Premium gasoline | $21.56 | 5 | 0 |
| 2022 | 15–24 | Premium gasoline | $20.66 | 4 | 0 |
| 2021 | 17–24 | Premium gasoline | $20.66 | 7 | 0 |
| 2020 | 16–23 | Premium gasoline | $21.56 | 13 | – |
| 2019 | 16–23 | Premium gasoline | $21.56 | 15 | – |
| 2018 | 16–22 | Premium gasoline | $22.54 | 14 | – |
| 2017 | 16–26 | Premium gasoline | $19.07 | 12 | – |
| 2016 | 15–26 | Premium gasoline | $19.07 | 9 | – |
| 2015 | 15–26 | Premium gasoline | $19.07 | 9 | – |
| 2014 | 18–20 | Premium gasoline | $24.80 | 3 | – |
| 2013 | 14–21 | Premium gasoline | $23.62 | 6 | – |
| 2012 | 14–21 | Premium gasoline | $23.62 | 6 | – |
| 2011 | 14–21 | Premium gasoline | $23.62 | 6 | – |
| 2010 | 13–21 | Premium gasoline | $23.62 | 6 | – |
| 2009 | 13–17 | Premium gasoline | $29.17 | 5 | – |
| 2008 | 13–16 | Premium gasoline | $31.00 | 5 | – |
| 2007 | 13–17 | Premium gasoline | $29.17 | 4 | – |
| 2006 | 13–19 | Premium gasoline | $26.10 | 8 | – |
| 2005 | 13–19 | Premium gasoline | $26.10 | 6 | – |
| 2004 | 13–19 | Premium gasoline | $26.10 | 6 | – |
| 2003 | 14–18 | Premium gasoline | $27.55 | 6 | – |
| 2002 | 16–18 | Premium gasoline | $27.55 | 4 | – |
| 2001 | 16–18 | Premium gasoline | $27.55 | 4 | – |
| 2000 | 17–18 | Premium gasoline | $27.55 | 2 | – |
| 1999 | 13–18 | Premium gasoline | $27.55 | 5 | – |
| 1998 | 13–18 | Premium gasoline | $27.55 | 7 | – |
| 1997 | 14–18 | Premium gasoline | $27.55 | 7 | – |
| 1996 | 14–18 | Premium gasoline | $27.55 | 7 | – |
| 1995 | 13–21 | Premium gasoline, Diesel | $23.62 | 8 | – |
| 1994 | 13–21 | Premium gasoline, Diesel | $23.62 | 7 | – |
Fuel economy: U.S. EPA fueleconomy.gov